Version 1.2

1.2.0

This version introduces multiprocessing to pVACtools. This significantly speeds up the execution of pVACseq, pVACfuse, and pVACvector. To turn on multiprocessing simply set the --n-threads parameter to the desired number of parallel processes. When running the tools using the IEDB RESTful API, we recommend to keep this number small (<5) as too many parallel calls to their API might lead to IEDB blocking jobs submitted from your IP address. It is recommended to use a standalone IEDB installation when running in multiprocessing mode. By default, multiprocessing is turned off.

This version also fixes a few bugs:

• In certain cases pVACvector was not calculating the junction scores correctly, leading to potentially finding a peptide order that would include high-binding junction epitopes or peptide orders that were not optimal. This issue has now been fixed.

• Due to a bug in our packaging code, the 1.1.x versions of pVACtools did not include the latest version of the pVACviz code. This version now includes the most up-to-date version of the graphical user interface.