Version 1.2


This version introduces multithreading to pVACtools. This significantly speeds up the execution of pVACseq, pVACfuse, and pVACvector. To turn on multithreading simply set the --n-threads parameter to the desired number of threads. This implementation is not CPU-bound. However, when running the tools using the IEDB RESTful API, we recommend to keep this number small (<5) as too many parallel calls to their API might lead to IEDB blocking jobs submitted from your IP address. It is recommended to use a standalone IEDB installation when running with multiple threads. By default, multithreading is turned off.

This version also fixes a few bugs:

  • In certain cases pVACvector was not calculating the junction scores correctly, leading to potentially finding a peptide order that would include high-binding junction epitopes or peptide orders that were not optimal. This issue has now been fixed.
  • Due to a bug in our packaging code, the 1.1.x versions of pVACtools did not include the latest version of the pVACviz code. This version now includes the most up-to-date version of the graphical user interface.